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Schematic diagram of Pb exposure promoting malignant progression of breast cancer via activation of the AKR1C3-NF-κB-MMP-2/MMP-9 axis (The pink arrow indicates promotion).

Journal: Biomedicines

Article Title: Environmental Lead Promotes Breast Cancer Migration and Invasion via the AKR1C3–NF-κB–MMP Axis

doi: 10.3390/biomedicines14020286

Figure Lengend Snippet: Schematic diagram of Pb exposure promoting malignant progression of breast cancer via activation of the AKR1C3-NF-κB-MMP-2/MMP-9 axis (The pink arrow indicates promotion).

Article Snippet: Recombinant MMP-9 protein (HY- P73300 , MedChemExpress) was activated with APMA (HY-148905, MedChemExpress) and then added to the cell culture medium at a concentration of 20 μg/mL.

Techniques: Activation Assay